Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity-Reference-Cited by-同舟云学术

Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity

Published:2020-01-01 Issue:1 Volume:12 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Camacho Raul C.¹,You Seohee¹,D’Aquino Katharine E.¹,Li Wenyu¹,Wang Yuanping¹,Gunnet Joseph¹,Littrell James¹,Qi Jian Shen¹,Kang Lijuan²,Jian Wenying²,MacDonald Mary³,Tat Timothy³,Steiner Derek³,Zhang Yue-Mei¹,Lanter James¹,Patch Raymond¹,Zhang Rui¹,Li Jiali³,Edavettal Suzanne³,Edwards Wilson³,Dinh Thai³,Wang Li Ying³,Connor Judy³,Hunter Michael³,Chi Ellen³,Swanson Ronald V.³,Leonard James N.¹,Case Martin A.³

Affiliation:

1. Janssen R&D, Spring House, PA, USA

2. Pharmacokinetics, Dynamics, and Metabolism, Janssen R&D, Spring House, PA, USA

3. Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USA

Funder

Janssen PRD

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2020.1794687