Characterization of highly concentrated antibody solution - A toolbox for the description of protein long-term solution stability
Author:
Affiliation:
1. Institute of Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany
2. Synthon Biopharmaceuticals B.V., Nijmegen, The Netherlands
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2017.1338222
Reference82 articles.
1. Biologic therapy for autoimmune diseases: an update
2. Antibody therapy of cancer
3. Challenges in the development of high protein concentration formulations
4. Solubility Challenges in High Concentration Monoclonal Antibody Formulations: Relationship with Amino Acid Sequence and Intermolecular Interactions
5. Forces controlling protein interactions: theory and experiment
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