Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors-Reference-Cited by-同舟云学术

Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors

Published:2017-10-24 Issue:1 Volume:10 Page:104-117
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Colley Caroline S.¹,Popovic Bojana¹,Sridharan Sudharsan¹,Debreczeni Judit E.²,Hargeaves David²,Fung Michael³,An Ling–Ling³,Edwards Bryan¹,Arnold Joanne¹,England Elizabeth¹,Eghobamien Laura⁴,Sivars Ulf⁵,Flavell Liz²,Renshaw Jonathan²,Wickson Kate²,Warrener Paul⁶,Zha Jingying⁶,Bonnell Jessica⁶,Woods Rob⁷,Wilkinson Trevor¹,Dobson Claire¹,Vaughan Tristan J.¹

Affiliation:

1. Antibody Discovery and Protein Engineering, MedImmune Ltd, Cambridge, UK

2. Discovery Sciences, AstraZeneca R&D, Cambridge, UK

3. Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, MD, USA

4. Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Cambridge, UK

5. Translational Biology, IMED RIA Biotech Unit, AstraZeneca, Gothenburg, Sweden

6. Infectious Diseases, MedImmune LLC, Gaithersburg, MD, USA

7. Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, MD, USA

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy