An efficient system for bioconjugation based on a widely applicable engineered O-glycosylation tag-Reference-Cited by-同舟云学术

An efficient system for bioconjugation based on a widely applicable engineered O-glycosylation tag

Published:2021-01-01 Issue:1 Volume:13 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Murray Thomas V.¹,Kozakowska-McDonnell Kasia²,Tibbles Adam¹,Taylor Annabel²,Higazi Daniel²,Rossy Emmanuel²,Rossi Alessandra³,Genapathy Sivaneswary⁴,Tamburrino Giulia¹,Rath Nicola⁵,Tigue Natalie⁴,Lindo Vivian²,Vaughan Tristan¹,Papworth Monika A.¹

Affiliation:

1. Biologics Engineering, R&D, AstraZeneca, Cambridge, UK

2. Biopharmaceutical Development, R&D, AstraZeneca, Cambridge, UK

3. Cardiovascular Renal and Metabolism, R&D, AstraZeneca, Cambridge, UK

4. Discovery Sciences, R&D, AstraZeneca, Cambridge, UK

5. Oncology R&D, AstraZeneca, Cambridge, UK

Funder

no funding associated with the work featured in this article

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1992068

Reference52 articles.

1. Site-specific bioconjugation and self-assembly technologies for multi-functional biologics: on the road to the clinic

2. Enzymatic strategies for (near) clinical development of antibody-drug conjugates

3. Preclinical and Clinical Advances of GalNAc-Decorated Nucleic Acid Therapeutics

4. Bioorthogonal Reactions for Labeling Proteins

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