Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal antibody targeting human CTLA-4 and PD-1-Reference-Cited by-同舟云学术

Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal antibody targeting human CTLA-4 and PD-1

Published:2021-01-01 Issue:1 Volume:13 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Chen Weimin¹,Pandey Madhu¹,Sun Hong¹,Rolong Andrea¹,Cao Mingyan²,Liu Dengfeng²,Wang Jihong²^ORCID,Zeng Lingmin³,Hunter Alan⁴,Lin Shihua¹

Affiliation:

1. Bioassay Development, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA

2. Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD, USA

3. Late Oncology Biometrics, AstraZeneca, Gaithersburg, MD, USA

4. Purification Process Sciences, AstraZeneca, Gaithersburg, MD, USA

Funder

AstraZeneca

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1914359

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