Identifying biophysical assays and in silico properties that enrich for slow clearance in clinical-stage therapeutic antibodies-Reference-Cited by-同舟云学术

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Identifying biophysical assays and in silico properties that enrich for slow clearance in clinical-stage therapeutic antibodies

Published:2021-01-01 Issue:1 Volume:13 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Grinshpun Boris¹^ORCID,Thorsteinson Nels²,Pereira Joao NS³,Rippmann Friedrich³,Nannemann David¹,Sood Vanita D.¹^ORCID,Fomekong Nanfack Yves¹^ORCID

Affiliation:

1. Discovery & Development Technologies, Drug Disposition & Design, EMD Serono Research & Development Institute, Inc, Billerica, MA, USA

2. Department of Scientific Services, Chemical Computing Group ULC, Montreal, Quebec, Canada

3. Discovery & Development Technologies, Drug Disposition & Design, Merck Healthcare KGaA, Darmstadt, Germany

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1932230

Reference55 articles.

1. Pharmacokinetics of Monoclonal Antibodies

2. FcRn: From Molecular Interactions to Regulation of IgG Pharmacokinetics and Functions

3. Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

4. Current progress in innovative engineered antibodies

5. DrugBank 5.0: a major update to the DrugBank database for 2018

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3. Molecular Modeling Methods in the Development of Affine and Specific Protein-Binding Agents;Biochemistry (Moscow);2024-08

4. Predicting human half-life for insulin analogs: An inter-drug approach;European Journal of Pharmaceutics and Biopharmaceutics;2024-08

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