A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy

Author:

Miao Xiaoniu1,Luo Yi1,Huang Xi2,Lee Suki M. Y.3,Yuan Zhijun1,Tang Yongzhou1,Chen Liandi1,Wang Chao1,Wu Fan1,Xu Yifeng1,Jiang Wenchao1,Gao Wei1,Song Xuedong1,Yan Yao1,Pang Tuling1,Chen Cheng1,Zou Yuefeng1,Fu Weihui1,Wan Liping1,Gilbert-Jaramillo Javier4,Knight Michael4,Tan Tiong Kit5,Rijal Pramila5,Townsend Alain5,Sun Joanne1,Liu Xiaolin1,James William4,Tsun Andy1,Xu Yingda1

Affiliation:

1. New Drug Discovery and Development, Biotheus Inc, Zhuhai, China

2. The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, China

3. New Drug Discovery and Development, Hong Kong Science and Technology Park, China

4. Sir William Dunn School of Pathology, University of Oxford, Oxford, UK

5. Centre for Translational Immunology, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

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