A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library
Author:
Affiliation:
1. GigaGen Inc., One Tower Place, Suite 750, South San Francisco, CA USA
2. Carterra Inc., 825 N 300 W, Suite C309, Salt Lake City, UT USA
3. Bristol-Myers Squibb, 700 Bay Road, Redwood City, CA USA
Funder
National Cancer Institute
National Science Foundation
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2018.1426422
Reference34 articles.
1. Development trends for human monoclonal antibody therapeutics
2. Fully human antibodies from transgenic mouse and phage display platforms
3. Continuous cultures of fused cells secreting antibody of predefined specificity
4. Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells
5. Germline VH/VL pairing in antibodies
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