Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold
Author:
Affiliation:
1. CEA, INRAE, Medicines and Healthcare Technologies Department, Université Paris-Saclay, SIMoS, France
2. Sanofi, Large Molecule Research, Vitry-sur-Seine, France
3. Sanofi, Integrated Drug Discovery, Vitry-sur-Seine, France
Funder
Sanofi
CIFRE fellowship
ANRT (National Association for Research and Technology
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2023.2175311
Reference58 articles.
1. Antibody and Antigen Contact Residues Define Epitope and Paratope Size and Structure
2. An Introduction to Epitope Mapping
3. Epitope Mapping of Antibody-Antigen Interactions with X-Ray Crystallography
4. Antibody Binding Epitope Mapping (AbMap) of Hundred Antibodies in a Single Run
5. Mapping Protein Binding Sites and Conformational Epitopes Using Cysteine Labeling and Yeast Surface Display
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