Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies

Author:

Dippel Andrew1,Gallegos Austin2,Aleti Vineela1,Barnes Arnita1,Chen Xiaoru3,Christian Elizabeth2,Delmar Jared2,Du Qun1,Esfandiary Reza2,Farmer Erika2,Garcia Andrew1,Li Qing41,Lin Jia1,Liu Weiyi53,Machiesky LeeAnn2,Mody Neil2,Parupudi Arun2,Prophet Meagan2,Rickert Keith1,Rosenthal Kim6,Ren Song3,Shandilya Harini1,Varkey Reena1,Wons Kevin2,Wu Yuling3,Loo Yueh-Ming6,Esser Mark T.6,Kallewaard Nicole L.76,Rajan Sarav1,Damschroder Melissa1,Xu Weichen82,Kaplan Gilad1ORCID

Affiliation:

1. Biologics Engineering, R&D, AstraZeneca, Gaithersburg, MD, USA

2. Biopharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, USA

3. Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gaithersburg, MD, USA

4. Hansoh Bio, Rockville, MD, USA

5. Pfizer, La Jolla, CA, USA

6. Vaccines and Immune Therapies, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA

7. Eli Lilly, Indianapolis, IN, USA

8. Biopharmaceutical Development, MacroGenics, Rockville, MD, USA

Funder

AstraZeneca

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

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