Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model-Reference-Cited by-同舟云学术

Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model

Published:2022-11-16 Issue:1 Volume:14 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Falck David¹^ORCID,Lechmann Martin²,Momčilović Ana¹^ORCID,Thomann Marco³,Koeleman Carolien A. M.¹,Jany Cordula²,Malik Sebastian³,Wuhrer Manfred¹^ORCID,Reusch Dietmar³

Affiliation:

1. Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands

2. Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Munich, Penzberg, Germany

3. Pharma Technical Development Europe, Roche Diagnostics GmbH, Penzberg, Germany

Funder

Dutch Research Council

Proteoform-resolved pharmacokinetics of biopharmaceuticals

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2022.2145929

Reference29 articles.

1. Building better monoclonal antibody-based therapeutics

2. Advances in antibody engineering for rheumatic diseases

3. Therapeutic antibodies: successes, limitations and hopes for the future

4. Pharmacokinetic and Pharmacodynamic Considerations in the Design of Therapeutic Antibodies

5. Fc glycans of therapeutic antibodies as critical quality attributes

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