Enhanced immunogenic potential of cancer immunotherapy antibodies in human IgG1 transgenic mice

Author:

Egli Jerome1ORCID,Heiler Stefan1,Weber Felix1,Steiner Guido1,Schwandt Timo1,Bray-French Katharine1,Klein Christian2,Fenn Sebastian3,Lotz Gregor P.3ORCID,Opolka-Hoffmann Eugenia3,Kraft Thomas E.3ORCID,Petersen Laetitia1,Moser Rebecca1,DeGeer Jonathan1,Siegel Michel1,Finke Daniela4ORCID,Bessa Juliana1ORCID,Iglesias Antonio1

Affiliation:

1. Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland

2. Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Roche Glycart AG, Schlieren, Switzerland

3. Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Penzberg, Germany

4. Department of Biomedicine and University Children’s Hospital of Basel, University of Basel, Basel, Switzerland

Funder

The author(s) reported there is no funding associated with the work featured in this article

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

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