Immunogenicity risk assessment for biotherapeutics through in vitro detection of CD134 and CD137 on T helper cells
Author:
Affiliation:
1. Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA
2. Department of Biostatistics, Genentech Inc, South San Francisco, CA, USA
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1898831
Reference44 articles.
1. Anti-Drug Antibodies: Emerging Approaches to Predict, Reduce or Reverse Biotherapeutic Immunogenicity
2. Immunogenicity of therapeutic proteins: Influence of aggregation
3. Impact of Product-Related Factors on Immunogenicity of Biotherapeutics
4. Pros and cons of the immunogenicity of monoclonal antibodies in cancer treatment: a lesson from autoimmune diseases
5. Lipid-Reduction Variability and Antidrug-Antibody Formation with Bococizumab
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