Off-target binding of an anti-amyloid beta monoclonal antibody to platelet factor 4 causes acute and chronic toxicity in cynomolgus monkeys-Reference-Cited by-同舟云学术

Off-target binding of an anti-amyloid beta monoclonal antibody to platelet factor 4 causes acute and chronic toxicity in cynomolgus monkeys

Author:

Loberg Lise I.¹^ORCID,Chhaya Meha²,Ibraghimov Alexander³,Tarcsa Edit⁴,Striebinger Andreas⁵,Popp Andreas⁶,Huang Lili²,Oellien Frank⁷,Barghorn Stefan⁵

Affiliation:

1. Development Sciences, AbbVie Inc., North Chicago, IL, USA

2. Global Biologics, AbbVie Inc., Worcester, MA, USA

3. Preclinical Safety, AbbVie Inc., Worcester, MA, USA

4. DMPK-BA, AbbVie Inc., Worcester, MA, USA

5. Discovery Biology, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany

6. Preclinical Safety, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany

7. Discovery Chemistry, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany

Funder

AbbVie sponsored

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

Reference23 articles.

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