Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose control-Reference-Cited by-同舟云学术

Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose control

Published:2021-01-01 Issue:1 Volume:13 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Liu Qiang¹,Garg Pankaj¹²,Hasdemir Burcu¹³,Wang Linya¹,Tuscano Emily¹,Sever Emily¹,Keane Erica¹,Hernandez Ana G Lujan¹,Yuan Tom Z.¹,Kwan Eric¹,Lai Joyce¹,Szot Greg⁴,Paruthiyil Sreenivasan⁴,Axelrod Fumiko¹,K. Sato Aaron¹

Affiliation:

1. Twist Biopharma, South San Francisco, CA, USA

2. Alamar Biosciences, Fremont, CA, USA

3. Catalyst Biosciences, South San Francisco, CA, USA

4. Diabetes Center, University of California San Francisco, San Francisco, CA, USA

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1893425

Reference43 articles.

1. G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

2. Drugability of Extracellular Targets: Discovery of Small Molecule Drugs Targeting Allosteric, Functional, and Subunit-Selective Sites on GPCRs and Ion Channels

3. Development of therapeutic antibodies for the treatment of diseases

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