Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform-Reference-Cited by-同舟云学术

Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform

Published:2015-05-27 Issue:4 Volume:7 Page:693-706
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Klarenbeek Alex,Mazouari Khalil El,Desmyter Aline,Blanchetot Christophe,Hultberg Anna,de Jonge Natalie,Roovers Rob C,Cambillau Christian,Spinelli Sylvia,Del-Favero Jurgen,Verrips Theo,de Haard Hans J,Achour Ikbel

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

http://www.tandfonline.com/doi/pdf/10.1080/19420862.2015.1046648

Reference48 articles.

1. Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans

2. Therapeutic antibodies: successes, limitations and hopes for the future

3. Replacing the complementarity-determining regions in a human antibody with those from a mouse

4. Reshaping human antibodies for therapy

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