Synthesis and Biophysical and Biological Evaluation of 2′-Modified Antisense Oligonucleotides
Author:
Affiliation:
1. a ISIS PHARMACEUTICALS , 2280 FARADAY AVENUE, CARLSBAD , CA , 92008 , USA
Publisher
Informa UK Limited
Subject
Genetics,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/07328319108046455
Reference1 articles.
Cited by 36 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Comparing In Vitro and In Vivo Activity of 2′-O-[2-(Methylamino)-2-oxoethyl]- and 2′-O-Methoxyethyl-Modified Antisense Oligonucleotides;Journal of Medicinal Chemistry;2008-04-10
2. Solution structure of DNA/RNA hybrid duplex with C8-propynyl 2′-deoxyadenosine modifications: Implication of RNase H and DNA/RNA duplex interaction;Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression;2007-01
3. Postsynthetic guanidinylation of primary amino groups in the minor and major grooves of oligonucleotides;Tetrahedron Letters;2002-10
4. Synthesis of 2‘-O-[2-[(N,N-Dimethylamino)oxy]ethyl] Modified Nucleosides and Oligonucleotides;The Journal of Organic Chemistry;2001-12-28
5. Hybridization of 2'-ribose modified mixed-sequence oligonucleotides: thermodynamic and kinetic studies;Nucleic Acids Research;2001-05-15
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