Synthesis of Several 2′-Deoxy-3-Alkyl(ARYL)-3-Deazaguanosines: Mild Alkylation of a Cyanomethyl Imidazole with Electrophiles
Author:
Publisher
Informa UK Limited
Subject
Genetics,Biochemistry
Reference10 articles.
1. New class of potent guanine antimetabolites. Synthesis of 3-deazaguanine, 3-deazaguanosine, and 3-deazaguanylic acid by a novel ring closure of imidazole precursors
2. Synthesis and antiviral/antitumor activities of certain 3-deazaguanine nucleosides and nucleotides
3. Synthesis of [2-14C]dezaguanine mesylate (6-amino-1,5-dihydro-4H-imidazo[4,5-c]pyridin-4-one-6-14C methanesulfonate), a new antitumor agent
4. Synthesis of 7- and 9-.beta.-D-ribofuranosides of 3-deaza-6-thioguanine and 3-deaza-2,6-diaminopurine by a novel ring closure of 4(5)-cyano-5(4)-cyanomethylimidazole .beta.-D-ribofuranosides
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1. C-3 halo and 3-methyl substituted 5′-nor-3-deazaaristeromycins: Synthesis and antiviral properties;Bioorganic & Medicinal Chemistry;2013-01
2. Electrophilic Fluorination of 5-(Cyanomethyl)imidazole-4-carboxylate Nucleosides: Facile Entry to 3-Fluoro-3-deazaguanosine Analogues;Synlett;2005-06-07
3. 8-Aza-3-deazaguanine modification strengthens the anomeric effect and affects other conformational preferences of modified guanine nucleosides;Journal of the Chemical Society, Perkin Transactions 2;2001
4. Synthesis Of Nucleosides;Organic Reactions;1999-11-08
5. Nucleosides and Nucleotides. 184. Synthesis and Conformational Investigation of Anti-Fixed 3-Deaza-3-halopurine Ribonucleosides1,2;The Journal of Organic Chemistry;1999-08-31
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