Synthesis, Antiproliferative, and Antiviral Evaluation of Certain Acyclic 6-Substituted Pyrrolo[2,3-D]-pyrimidine Nucleoside Analogs Related to Sangivamycin and Toyocamycin-Reference-Cited by-同舟云学术

Synthesis, Antiproliferative, and Antiviral Evaluation of Certain Acyclic 6-Substituted Pyrrolo[2,3-D]-pyrimidine Nucleoside Analogs Related to Sangivamycin and Toyocamycin

Published:1992-09 Issue:8 Volume:11 Page:1507-1527
ISSN:0732-8311
Container-title:Nucleosides and Nucleotides
language:en
Short-container-title:Nucleosides and Nucleotides

Author:

Swayze Eric E.,Shannon William M.,Buckheit Robert W.,Wotring Linda L.,Drach John C.,Townsend Leroy B.

Publisher

Informa UK Limited

Subject

Genetics,Biochemistry

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4. A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2

5. Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1.

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