Synthesis and Conformational Studies of New Purine Isodideoxynucleosides
Author:
Affiliation:
1. a Department of Chemistry , The University of Iowa , Iowa City , Iowa , 52242
Publisher
Informa UK Limited
Subject
Genetics,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/07328319608002371
Reference52 articles.
1. 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.
2. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.
3. Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro.
4. In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine
5. Antiviral Activity Spectrum and Target of Action of Different Classes of Nucleoside Analogues
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