(18R)-Variabilin from the SpongeIrcinia felix

Author:

Martinez Alejandro,Duque Carmenza,Sato Naoko,Tanaka Reiko,Fujimoto Yoshinori

Publisher

Informa UK Limited

Subject

Molecular Medicine

Reference9 articles.

1. Variabilin, an antibiotic from the sponge, ircinia variabilis

2. Variabilin and Related Compounds from a Sponge of the Genus Sarcotragus

3. On the Stereochemistry and Biogenesis of C21 Linear Furanoterpenes in Ircinia sp.

4. 1H-NMR (CDCl3, 500MHz): δ 1.05 (3H, d,J,=6.6 Hz, 19-H3), 1.55 (3H, s, 14-H3), 1.58 (3H, s, 9-H3), 1.82 (3H, s, 25-H3), 2.36 (3H, s, AcO), 2.82 (1H, m, 28-H), 5.04 (1H, d,J,=10.8 Hz, 20-H), 5.08 (1H, t,J,=6.8 Hz, 12-H), 5.17 (1H, t,J,=6.8 Hz, 7-H), 6.28 (1H, s, 2-H), 7.20 (1H, s, 4-H), 7.33 (1H, s, 1-H);13C-NMR (CDCl3, 125MHz) δ 8.4 (C-25), 15.8 (C-14), 16.0 (C-9), 20.4 (C-19), 20.6 (CH3CO), 25.0 (C-5), 25.6 (C-16), 26.5 (C-11), 28.4 (C-6), 31.1 (C-18), 36.6 (C-17), 39.5 (C-15), 39.7 (C-10), 111.1 (C-2), 114.7 (C-23), 116.6 (C-20), 123.7 (C-7), 124.4 (C-12), 125.0 (C-3), 134.8 (C-13), 135.7 (C-8), 138.8 (C-4), 142.3 (C-21), 142.5 (C-1), 154.3 (C-22), 165.4 (CH3CO), 168.6 (C-24)

5. A greatly improved procedure for ruthenium tetroxide catalyzed oxidations of organic compounds

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1. Sesterterpenoids;Progress in the Chemistry of Organic Natural Products 111;2020

2. Furanosesterterpenes from the Guangxi sponge Biemna fortis Topsent;Biochemical Systematics and Ecology;2018-10

3. New Cytotoxic 24-Homoscalarane Sesterterpenoids from the Sponge Ircinia felix;International Journal of Molecular Sciences;2015-09-11

4. New Scalarane Sesterterpenoids from the Formosan Sponge Ircinia felix;Marine Drugs;2015-07-14

5. Porifera (Sponges)-5;Encyclopedia of Marine Natural Products;2014-08-07

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