Stable Transfection of Dihydrodiol Dehydrogenase in MCF-7 Breast Carcinoma Cells Promotes Polycyclic Aromatic Hydrocarbon-O-Quinone Formation which Leads to Cell Death
Author:
Publisher
Informa UK Limited
Subject
Materials Chemistry,Organic Chemistry,Polymers and Plastics
Link
http://www.tandfonline.com/doi/pdf/10.1080/10406639908020588
Reference24 articles.
1. Benzo[a]pyrene-nucleic acid derivative found in vivo: structure of a benzo[a]pyrenetetrahydrodiol epoxide-guanosine adduct
2. Expanded Analysis of Benzo[a]pyrene−DNA Adducts Formed in Vitro and in Mouse Skin: Their Significance in Tumor Initiation
3. Spectroscopic identification of ortho-quinones as the products of polycyclic aromatic trans-dihydrodiol oxidation catalyzed by dihydrodiol dehydrogenase. A potential route of proximate carcinogen metabolism.
4. Generation of Reactive Oxygen Species during the Enzymatic Oxidation of Polycyclic Aromatic Hydrocarbon trans-Dihydrodiols Catalyzed by Dihydrodiol Dehydrogenase
5. Reactivity of benzo[a]pyrene-7,8-dione with DNA. Evidence for the formation of deoxyguanosine adducts
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Synthesis and Characterization of Polycyclic Aromatic Hydrocarbon o-Quinone Depurinating N7-Guanine Adducts;Chemical Research in Toxicology;1999-01-29
2. Dihydrodiol Dehydrogenases and Polycyclic Aromatic Hydrocarbon Activation: Generation of Reactive and Redox Active o-Quinones;Chemical Research in Toxicology;1998-12-10
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