Metabolism of Benzo[a]pyrene by Seven cDNA Expressed Human Cytochromes P450
Author:
Publisher
Informa UK Limited
Subject
Materials Chemistry,Organic Chemistry,Polymers and Plastics
Link
http://www.tandfonline.com/doi/pdf/10.1080/10406639408014706
Reference33 articles.
1. Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes.
2. Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides.
3. Benzo[ a ]pyrene Diol Epoxides: Mechanism of Enzymatic Formation and Optically Active Intermediates
4. Guengerich, F. P. 1987. “Mammalian Cytochrome P450”. Edited by: Guengerich, F. P. Vol. 1, 1–54. Boca Raton, FL: CRC Press, Inc.
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1. Importance of CYP1A1 and CYP1B1 in bioactivation of benzo[a]pyrene in human lung cell lines;Toxicology Letters;2010-02
2. Interaction of PAH-related compounds with the α and β isoforms of the estrogen receptor;Toxicology Letters;2001-05
3. Hydroxylated Benzo[a]pyrene Metabolites Are Responsible for in Vitro Estrogen Receptor-Mediated Gene Expression Induced by Benzo[a]pyrene, but Do Not Elicit Uterotrophic Effects in Vivo;Toxicological Sciences;2001-02-01
4. Inhibition of the contraction of the ductus arteriosus to oxygen by 1-aminobenzotriazole, a mechanism-based inactivator of cytochrome P450;British Journal of Pharmacology;1996-04
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