Oral ferroportin inhibitor vamifeport for improving iron homeostasis and erythropoiesis in β-thalassemia: current evidence and future clinical development

Author:

Porter John1ORCID,Taher Ali2ORCID,Viprakasit Vip3ORCID,Kattamis Antonis4ORCID,Coates Thomas D5ORCID,Garbowski Maciej6ORCID,Dürrenberger Franz7,Manolova Vania8ORCID,Richard Frank9ORCID,Cappellini M. Domenica10ORCID

Affiliation:

1. Professor of Haematology, Department of Haematology, University College London, Consultant in Haematology, University College London Hospitals and Head of Joint UCLH and Whittington Hospital Red Cell Unit, London, UK

2. Professor of Medicine, Hematology and Oncology, Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon

3. Professor of Pediatrics, Director, Thalassemia Research Program, Director, SiCORE in Advanced Cell & Gene Therapy Center (SiCORE-ACGT), Division of Hematology and Oncology, Department of Pediatrics & Siriraj Thalassemia Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

4. Professor of Pediatric Hematology-Oncology, Division of Pediatric Hematology-Oncology, First Department of Pediatrics, National and Kapodistrian University of Athens, Athens, Greece

5. Section Head, Hematology, Cancer and Blood Disease Institute, Professor of Pediatrics and Pathology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, USA

6. Clinical Research Fellow, Department of Haematology, University College London Cancer Institute, London, UK

7. Head of Chemical and Preclinical R&D, Vifor (International) AG, Chemical and Preclinical Research and Development, St. Gallen, Switzerland

8. Head of Biology R&D, Vifor (International) AG, Chemical and Preclinical Research and Development, St. Gallen, Switzerland

9. Clinical Research Director, Vifor Pharma AG, Glattbrugg, Switzerland

10. Professor of Internal Medicine, Department of Clinical Sciences and Community, University of Milan, Milan, Italy

Funder

Vifor Pharma AG, Glattbrugg, Switzerland

Publisher

Informa UK Limited

Subject

Hematology

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