Microsimulation to compare activity-related bleed risks between pharmacokinetic-guided rurioctocog alfa pegol prophylaxis and emicizumab
Author:
Affiliation:
1. Global Evidence and Outcomes, Takeda Development Center Americas, Inc, Cambridge, MA, USA
2. Health Economics & Outcomes Research, Stratevi, Santa Monica, CA, USA
Publisher
Informa UK Limited
Subject
Hematology
Link
https://www.tandfonline.com/doi/pdf/10.1080/17474086.2023.2162498
Reference17 articles.
1. WFH Guidelines for the Management of Hemophilia, 3rd edition
2. A 6-year follow-up of dosing, coagulation factor levels and bleedings in relation to joint status in the prophylactic treatment of haemophilia
3. Factor VIII requirement to maintain a target plasma level in the prophylactic treatment of severe hemophilia A: influences of variance in pharmacokinetics and treatment regimens
4. Baxalta Innovations GmbH. ADYNOVI (rurioctocog alfa pegol). Summary of product characteristics. 2022 [cited 2023 Jan 04]. Available from 2022 Nov 17: https://www.ema.europa.eu/en/documents/product-information/adynovi-epar-product-information_en.pdf
5. Baxalta US Inc. ADYNOVATE (antihemophilic factor [recombinant], PEGylated). Highlights of prescribing information. 2021 [cited 2023 Jan 4]. Available 2021 Jun: https://www.shirecontent.com/PI/PDFs/ADYNOVATE_USA_ENG.pdf
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