Hypermethylation of the OPRM1 and ALDH2 promoter regions in Chinese Han males with alcohol use disorder in Yunnan Province

Author:

Liu Linlin12,Yang Xiaopei13,Zhao Fei14,Gao Changqing56,Zhang Ning1,Bao Jianjun78,Li Kuan1,Zhang Xulan78,Lu Xiaoxiao1,Ruan Ye78,Zhong Shurong12

Affiliation:

1. School of Forensic Medicine, Kunming Medical University, Kunming, China

2. Forensic biology identification laboratory, Judicial Identification Center of Kunming Medical University, Kunming, China

3. Department of basic medicine, Chuxiong Medical and Pharmaceutical College, Chuxiong, China

4. Forensic Lab 1, Jiangxi Shenzhou Judicial Identification Center, Nanchang, China

5. Children's mental department, The Mental Hospital of Yunnan Province, Kunming, China

6. Children's mental department, Alcohol and Drug Dependence Treatment Department, Mental Health Center Affiliated With Kunming Medical University, Kunming, China

7. Alcohol and Drug Dependence Treatment Department, The Mental Hospital of Yunnan Province, Kunming, China

8. Alcohol and Drug Dependence Treatment Department, Mental Health Center Affiliated With Kunming Medical University, Kunming, China

Funder

the National Natural Science Foundation of China

Top 100 Young and Middle-Aged Academic and Technical Backbone Projects of Kunming Medical University

Applied Basic Research Joint Special Fund from the Department of Science and Technology of Yunnan Province-Kunming Medical University

the Major Special Project in the Field of Biomedicine of Yunnan Provincial Department of Science and Technology

Major Special Project in the Field of Biomedicine of Yunnan Provincial Department of Science and Technology

Publisher

Informa UK Limited

Subject

Psychiatry and Mental health,Clinical Psychology,Medicine (miscellaneous)

Reference45 articles.

1. Diagnostic and Statistical Manual of Mental Disorders

2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-IV). 4th. Washington, DC: American Psychiatric Association;1994. p. 194–204

3. World Health Organization. The ICD-10 classification of mental and behavioural disorders: diagnostic criteria for research. Geneva: World Health Organization; 1993. p. 70–83.

4. DNA methylation age is accelerated in alcohol dependence

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