Fgd5 is a Rac1-specific Rho GEF that is selectively inhibited by aurintricarboxylic acid-Reference-Cited by-同舟云学术

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Fgd5 is a Rac1-specific Rho GEF that is selectively inhibited by aurintricarboxylic acid

Published:2019-10-10 Issue:2 Volume:12 Page:147-160
ISSN:2154-1248
Container-title:Small GTPases
language:en
Short-container-title:Small GTPases

Author:

Park Sally¹,Guo Yitian²,Negre Judeah¹,Preto Jordane³^ORCID,Smithers Cameron C.⁴,Azad Abul Kalam⁵,Overduin Michael⁴,Murray Allan G.⁵,Eitzen Gary¹²

Affiliation:

1. Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada

2. Department of Medicine-Division of Pulmonary Medicine, University of Alberta, Edmonton, Alberta, Canada

3. Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

4. Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada

5. Department of Medicine, Division of Nephrology, University of Alberta, Edmonton, Alberta, Canada

Funder

Canadian Cancer Society Research Institute

Natural Sciences and Engineering Research Council of Canada

Publisher

Informa UK Limited

Subject

Cell Biology,Biochemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/21541248.2019.1674765

Reference41 articles.

1. Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: A putative RhoRac guanine nucleotide exchange factor

2. Mutations in FGD4 Encoding the Rho GDP/GTP Exchange Factor FRABIN Cause Autosomal Recessive Charcot-Marie-Tooth Type 4H

3. Peripheral Nerve Demyelination Caused by a Mutant Rho GTPase Guanine Nucleotide Exchange Factor, Frabin/FGD4

4. FGD5 Regulates VEGF Receptor-2 Coupling to PI3 Kinase and Receptor Recycling

5. FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation

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1. Ang-1 and VEGF: central regulators of angiogenesis;Molecular and Cellular Biochemistry;2024-04-23

2. Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia;Diabetologia;2023-11-28

3. FGD5 as a novel prognostic biomarker and its association with immune infiltrates in lung adenocarcinoma;BIOCELL;2023

4. Exosomes derived from dental pulp stem cells accelerate cutaneous wound healing by enhancing angiogenesis via the Cdc42/p38 MAPK pathway;International Journal of Molecular Medicine;2022-10-31

5. FGD5 marks a subpopulation of hematopoietic stem and progenitor cells that resist interferon-γ-mediated differentiation;Experimental Hematology;2022-08

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