1. Department of Medicine, Centro Hospitalar São João, Porto, Portugal
2. FMUP, Faculty of Medicine, University of Porto, Porto, Portugal
3. LPCC, Research Department Portuguese League against Cancer (Liga Portuguesa Contra O Cancro, Núcleo Regional Do Norte), Porto, Portugal
4. CEBIMED, Faculty of Health Sciences, Fernando Pessoa University, Porto, Portugal
5. Molecular Oncology and Viral Pathology Group, IPO-Porto Research Center (CI-IPOP), Portuguese Institute of Oncology of Porto (Ipo-porto), Porto, Portugal