Dexmedetomidine inhibits the NF-κB pathway and NLRP3 inflammasome to attenuate papain-induced osteoarthritis in rats-Reference-Cited by-同舟云学术

Dexmedetomidine inhibits the NF-κB pathway and NLRP3 inflammasome to attenuate papain-induced osteoarthritis in rats

Published:2019-01-01 Issue:1 Volume:57 Page:649-659
ISSN:1388-0209
Container-title:Pharmaceutical Biology
language:en
Short-container-title:Pharmaceutical Biology

Author:

Cheng Fang¹,Yan Feng-Feng¹,Liu Yue-Peng²,Cong Yan³,Sun Ke-Fu⁴,He Xue-Ming⁵

Affiliation:

1. Department of Pain Clinic, The Affiliated Lianyungang Oriental Hospital of Xuzhou Medical University, Lianyungang, China;

2. Center for Clinical Research and Translational Medicine, The Affiliated Lianyungang Oriental Hospital of Xuzhou Medical University, Lianyungang, China;

3. Department of Traditional Chinese and Western Medicine, The Affiliated Lianyungang Oriental Hospital of Xuzhou Medical University, Lianyungang, China;

4. Department of Orthopedic, The Affiliated Lianyungang Oriental Hospital of Xuzhou Medical University, Lianyungang, China;

5. Department of Geratology, The Affiliated Lianyungang Oriental Hospital of Xuzhou Medical University, Lianyungang, China

Publisher

Informa UK Limited

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/13880209.2019.1651874

Reference52 articles.

1. The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

2. Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

3. Synovial tissue inflammation in early and late osteoarthritis

4. Dexmedetomidine

5. Stress-induced cartilage degradation does not depend on the NLRP3 inflammasome in human osteoarthritis and mouse models

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