Cryptotanshinone enhances the efficacy of Bcr-Abl tyrosine kinase inhibitors via inhibiting STAT3 and eIF4E signalling pathways in chronic myeloid leukaemia
Author:
Affiliation:
1. School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China
2. The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
Funder
National Natural Science Foundation of China
Zhejiang Provincial Natural Science Foundation of China
Publisher
Informa UK Limited
Subject
Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/13880209.2021.1944224
Reference37 articles.
1. STAT3 in cancer: A double edged sword
2. Combination of Imatinib with CXCR4 Antagonist BKT140 Overcomes the Protective Effect of Stroma and Targets CML In Vitro and In Vivo
3. The significance of angiogenesis for predicting optimal therapeutic response in chronic myeloid leukaemia patients
4. Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors
5. Erratum: Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia
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