The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial-Reference-Cited by-同舟云学术

The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial

Published:2021-04-25 Issue:1 Volume:59 Page:484-493
ISSN:1388-0209
Container-title:Pharmaceutical Biology
language:en
Short-container-title:Pharmaceutical Biology

Author:

Gou Zhong-Ping¹,Zhao Yun-Li²³,Zou Lin-Ling¹,Wang Ying¹,Shu Shi-Qing¹,Zhu Xiao-Hong¹,Zheng Li¹,Shen Qi¹,Luo Zhu¹,Miao Jia¹,Wang Yong-Sheng¹,Luo Xiao-Dong²³,Feng Ping¹

Affiliation:

1. Institute of Drug Clinical Trials, West China Hospital, Sichuan University, Chengdu, People’s Republic of China

2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People’s Republic of China

3. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Provincial Center for Research & Development of Natural Products; School of Chemical Science and Technology, Yunnan University, Kunming, People's Republic of China

Funder

Yunnan Major Science and Technology Project

National Key Research and Development Program of China

Major Specific Project of Sichuan Province

Publisher

Informa UK Limited

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/13880209.2021.1893349

Reference52 articles.

1. International Conference on Harmonization. 2002. E1-E10 International Conference on Harmaonisation of technical requirements for registration of pharmaceuticals for human use ICH harmonised tripartite guideline. Washington DC: The European Medicines Agency; p. 69–72.

2. A New Type of Monoterpenoid Indole Alkaloid Precursor from Alstonia rostrata

3. Unique Monoterpenoid Indole Alkaloids from Alstonia scholaris

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