Identification of cytochrome P450 isoenzymes involved in the metabolism of 23-hydroxybetulinic acid in human liver microsomes
Author:
Affiliation:
1. Department of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China
2. Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
Funder
National Natural Science Foundation of China
Natural Science Foundation of Jiangxi Province
China ‘Creation of New Drugs’ Key Technology Projects
Publisher
Informa UK Limited
Subject
Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/13880209.2019.1701500
Reference12 articles.
1. Silver complexation and tandem mass spectrometry for differentiation of triterpenoid saponins from the roots ofPulsatilla chinensis(Bunge) Regel
2. Bioactivation of herbal constituents: simple alerts in the complex system
3. Cytochrome P450s and other enzymes in drug metabolism and toxicity
4. 23-Hydroxybetulinic acid-mediated apoptosis is accompanied by decreases in bcl-2 expression and telomerase activity in HL-60 Cells
5. High-Throughput Mass Spectrometric Cytochrome P450 Inhibition Screening
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