In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase for treatment of Falciparum malaria-Reference-Cited by-同舟云学术

In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase for treatment of Falciparum malaria

Published:2016-09-21 Issue:1 Volume:55 Page:19-32
ISSN:1388-0209
Container-title:Pharmaceutical Biology
language:en
Short-container-title:Pharmaceutical Biology

Author:

Wadood Abdul¹,Ghufran Mehreen¹,Hassan Syed Fahad²,Khan Huma¹,Azam Syed Sikandar³,Rashid Umer⁴

Affiliation:

1. Department of Biochemistry, Abdul Wali Khan University Mardan, Mardan, Pakistan;

2. Department of Pharmacy, University of Lahore, Lahore, Pakistan;

3. Department of Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan;

4. Department of Chemistry, COMSAT, Abbatabad, Pakistan

Publisher

Informa UK Limited

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/13880209.2016.1225778

Reference65 articles.

1. Novel antimalarial drug targets: hope for new antimalarial drugs

2. Molecular conformation and biological activity of central nervous system active drugs

3. Proteomic analysis of Plasmodium falciparum parasites from patients with cerebral and uncomplicated malaria

4. Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model*

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