1. Graduate Program in Pharmaceutical Sciences, School of Pharmacy, Federal University of Rio de Janeiro, RJ, Brazil;
2. Department of Natural Products, Farmanguinhos, FIOCRUZ, RJ, Brazil;
3. Department of General Microbiology, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro, RJ, Brazil;
4. Laboratory of Structural Biology and Electron Microscopy Platform Rudolf Barth, Oswaldo Cruz Institute (IOC), RJ, Brazil;
5. Department of Botany, Institute of Biology, Federal University of Rio de Janeiro, RJ, Brazil;
6. Department of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, RJ, Brazil