Magnetic resonance imaging and diffusion tensor analysis of lymphomatoid granulomatosis of the brain

Author:

Kiryu S.1,Okubo T.1,Takeuchi K.1,Inoue Y.1,Endo T.1,Odawara T.1,Nakamura T.1,Aoki S.1,Ohtomo K.1

Affiliation:

1. Department of Radiology, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Department of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan; Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Department of Radiology, Graduate School and Faculty of Medicine, University of Tokyo, Tokyo, Japan

Abstract

We present the case of a 56-year-old man suffering from acquired immune deficiency syndrome associated with lymphomatoid granulomatosis. Magnetic resonance imaging performed because of convulsions revealed an ill-defined frontal mass showing hypointense on T1WI and slightly hypointense on T2WI with surrounding edema. An elevated uptake was found on Tl-201 single photo emission computed tomography consistent with a central nervous system lymphoma. However, the apparent diffusion coefficient ratio calculated from diffusion–tensor acquisitions was 1.53 and was higher than that of lymphomas in previous reports. Stereotactic brain biopsy was performed and lymphomatoid granulomatosis was confirmed.

Publisher

SAGE Publications

Subject

Radiology Nuclear Medicine and imaging,General Medicine,Radiological and Ultrasound Technology

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