Design of tuberculosis vaccine trials under financial constraints

Author:

García-Basteiro Alberto L.123,Ruhwald Morten4,Lange Christoph56789

Affiliation:

1. Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique

2. ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat de Barcelona, Barcelona, Spain

3. Amsterdam Institute for Global Health and Development (AIGHD), Amsterdam, The Netherlands

4. Human immunology, Dept. of infectious disease immunology, Statens Serum Institut, Copenhagen, Denmark

5. Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany

6. German Center for Infection Research, Clinical Tuberculosis Center, Borstel, Germany

7. International Health/Infectious Diseases, University of Lübeck, Lübeck, Germany

8. Department of Medicine, Karolinska Institute, Stockholm, Sweden

9. Department of Internal Medicine, University of Namibia School of Medicine, Windhoek, Namibia

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Immunology

Reference20 articles.

1. WHO/HTM/TB/2015.22. Global tuberculosis report. 2015. Geneva (Switzerland): World Health Organization, 2015.

2. WHO's new End TB Strategy

3. Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis

4. Tuberculosis Vaccine Initiative (TBVI). Pipeline of Vaccines. 2015. Available from: http://www.tbvi.eu/what-we-do/pipeline-of-vaccines/

5. Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial

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