Effectiveness of primary series, first, and second booster vaccination of monovalent mRNA COVID-19 vaccines against symptomatic SARS-CoV-2 infections and severe diseases during the SARS-CoV-2 omicron BA.5 epidemic in Japan: vaccine effectiveness real-time surveillance for SARS-CoV-2 (VERSUS)

Author:

Maeda Haruka12,Saito Nobuo3,Igarashi Ataru45,Ishida Masayuki6,Terada Mayumi7,Masuda Shingo89,Osawa Ryosuke10,Hosokawa Naoto10,Nakashima Kei11,Kamura Hiroshi12,Imura Haruki13,Inoue Hiroki13,Matsuzaka Suguru14,Sugimoto Yukihiro15,Kuwamitsu Osamu16,Motohashi Iori17,Morikawa Toru18,Oda Rentaro19,Hoshina Yuiko19,Matono Takashi2021,Teshigahara Osamu22,Sando Eiichiro2324,Asami Sadaharu25,Kudo Satoshi26,Akizuki Noboru27,Muto Yoshikazu28,Hayakawa Tomoichiro29,Kishaba Tomoo30,Ohara Yasuji31,Kubo Yoshinao29,Suzuki Motoi32,Morimoto Konosuke1

Affiliation:

1. Department of Respiratory Infections, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan

2. Department of Clinical Tropical Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

3. Kenya Research Station, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan

4. School of Data Science, Yokohama City University School of Medicine, Kanagawa, Japan

5. Department of Health Economics and Outcomes Research, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan

6. Department of Infectious Disease Medicine, Chikamori Hospital, Kochi, Japan

7. Department of Internal Medicine, Nijigaoka Hospital, Nagasaki, Japan

8. Department of Infectious Diseases, Nagasaki University Hospital, Nagasaki, Japan

9. Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan

10. Department of Infectious Diseases, Kameda Medical Center, Chiba, Japan

11. Department of Pulmonology, Kameda Medical Center, Chiba, Japan

12. Loco Clinic Nakameguro, Tokyo, Japan

13. Department of Infectious Disease Medicine, Rakuwakai Otowa Hospital, Kyoto, Japan

14. Department of General Medicine, Fukuoka Seishukai Hospital, Fukuoka, Japan

15. Department of Respiratory Medicine, Fukuoka Seishukai Hospital, Fukuoka, Japan

16. Gohongi Clinic, Tokyo, Japan

17. Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Kawasaki, Japan

18. Department of General Medicine, Nara City Hospital, Nara, Japan

19. Department of Infectious Diseases, Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, Japan

20. Department of Infectious Diseases, Aso Iizuka Hospital, Fukuoka, Japan

21. Division of Infectious Disease and Hospital Epidemiology, Saga University Hospital, Saga, Japan

22. Mizuho Street Clinic, Aichi, Japan

23. Department of General Internal Medicine and Clinical Infectious Diseases, Kita-Fukushima Medical Center, Date, Japan

24. Department of General Internal Medicine and Clinical Infectious Diseases, Fukushima Medical University, Fukushima, Japan

25. Department of Cardiology, Musashino Tokushukai Hospital, Tokyo, Japan

26. Department of Nursing, Musashino Tokushukai Hospital, Tokyo, Japan

27. Department of Emergency Medicine, Musashino Tokushukai Hospital, Tokyo, Japan

28. Department of Infectious Diseases, Tosei General Hospital, Seto, Japan

29. Hayakawa Internal Medicine Clinic, Fukuoka, Japan

30. Department of Respiratory Medicine, Okinawa Chubu Hospital, Okinawa, Japan

31. Jin Sakura Clinic, Nagoya, Japan

32. Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan

Funder

Ministry of Health, Labour and Welfare

Publisher

Informa UK Limited

Reference37 articles.

1. Ministry of Health Labour and Welfare. Asymptomatic carriers of SARS-COV-2 in airport quarantine. 2021 Nov 30 [cited 2023 Nov 20]. Available from: https://www.mhlw.go.jp/stf/newpage_22507.html

2. Ministry of Health Labour and Welfare. SARS-CoV-2 open data. [cited 2023 Nov 20]. Available from: https://www.mhlw.go.jp/stf/covid-19/open-data.html

3. National Institute of Infectious Diseases. SARS-CoV-2 variants. [cited 2023 Nov 20]. Available from: https://www.niid.go.jp/niid/ja/2019-ncov/2624-flu/12054-flu2-1-2.html

4. Ministry of Health Labour and Welfare. Materials at the 32nd meeting of the subcommittee on immunization and vaccine of the health science council (held on April 27 2022). [cited 2023 Nov 20.] Available from: https://www.mhlw.go.jp/stf/newpage_25379.html

5. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

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