Identification of isoaspartate-modified transthyretin as potential target for selective immunotherapy of transthyretin amyloidosis

Author:

Köppen Janett1,Kleinschmidt Martin1,Morawski Markus2,Rahfeld Jens-Ulrich1,Wermann Michael1,Cynis Holger13,Hegenbart Ute4,Daniel Christoph5,Roßner Steffen2,Schilling Stephan16,Schulze Anja16

Affiliation:

1. Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), Germany

2. Paul Flechsig Institute – Center of Neuropathology and Brain Research, Leipzig, Germany

3. Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

4. Department of Hematology, Oncology and Rheumatology, Amyloidosis Center, University Hospital, Heidelberg, Germany

5. Department of Nephropathology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany

6. Faculty of Applied Biosciences and Bioprocess Technology, Anhalt University of Applied Sciences, Köthen, Germany

Funder

the Europäischer Fonds für regionale Entwicklung (EFRE) and Investitionsbank Sachsen-Anhalt

Publisher

Informa UK Limited

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