Circular RNA Sirtuin1 represses pulmonary artery smooth muscle cell proliferation, migration and autophagy to ameliorate pulmonary hypertension via targeting microRNA-145-5p/protein kinase-B3 axis
Author:
Affiliation:
1. Department of Respiratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan Province, China
2. Zhibang Biological Laboratory, Guangzhou Science City Incubation Base, Guangzhou City, Guangdong Province, 510000, China
Funder
Henan Medical Science and Technology Research Plan
Natural Science Foundation of Henan Province
Key Research Projects of Henan Higher Education Institutions
Henan Science and Technology Research Program
Publisher
Informa UK Limited
Subject
Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology
Link
https://www.tandfonline.com/doi/pdf/10.1080/21655979.2022.2036302
Reference34 articles.
1. Hsa_circ_0002062 Promotes the Proliferation of Pulmonary Artery Smooth Muscle Cells by Regulating the Hsa-miR-942-5p/CDK6 Signaling Pathway
2. Circular RNA‐HIPK3 regulates human pulmonary artery endothelial cells function and vessel growth by regulating microRNA‐328‐3p/STAT3 axis
3. Up‐regulation of circRNA_0068481 promotes right ventricular hypertrophy in PAH patients via regulating miR‐646/miR‐570/miR‐885
4. circ-Sirt1 controls NF-κB activation via sequence-specific interaction and enhancement of SIRT1 expression by binding to miR-132/212 in vascular smooth muscle cells
5. Circ-SIRT1 inhibits cardiac hypertrophy via activating SIRT1 to promote autophagy
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