Fraxetin down-regulates polo-like kinase 4 (PLK4) to inhibit proliferation, migration and invasion of prostate cancer cells through the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway-Reference-Cited by-同舟云学术

Fraxetin down-regulates polo-like kinase 4 (PLK4) to inhibit proliferation, migration and invasion of prostate cancer cells through the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway

Published:2022-04-01 Issue:4 Volume:13 Page:9345-9356
ISSN:2165-5979
Container-title:Bioengineered
language:en
Short-container-title:Bioengineered

Author:

Ma Zheng¹,Sun Yanfang²,Peng Weixing³

Affiliation:

1. Department of Urology, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou City, China

2. Department of Ultrasound, Guanggu Branch of Wuhan Third Hospital, Wuhan City, China

3. Department of Urology, Zhoushan Branch Shanghai Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Zhoushan City, China

Funder

autho

Publisher

Informa UK Limited

Subject

Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology

Link

https://www.tandfonline.com/doi/pdf/10.1080/21655979.2022.2054195

Reference30 articles.

1. Fraxetin inhibits interleukin-1β-induced apoptosis, inflammation, and matrix degradation in chondrocytes and protects rat cartilage in vivo

2. Fraxetin Suppresses Cell Proliferation and Induces Apoptosis through Mitochondria Dysfunction in Human Hepatocellular Carcinoma Cell Lines Huh7 and Hep3B

3. Fraxetin inhibits the growth of colon adenocarcinoma cells via the Janus kinase 2/signal transducer and activator of transcription 3 signalling pathway

4. The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation

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