Estimation of polymorphisms in the drug-metabolizing enzyme, cytochrome P450 2C19 gene in six major ethnicities of Pakistan-Reference-Cited by-同舟云学术

Estimation of polymorphisms in the drug-metabolizing enzyme, cytochrome P450 2C19 gene in six major ethnicities of Pakistan

Published:2021-01-01 Issue:1 Volume:12 Page:4442-4451
ISSN:2165-5979
Container-title:Bioengineered
language:en
Short-container-title:Bioengineered

Author:

Ahmed Sagheer¹^ORCID,Gul Saima²,Akhlaq Muhammad³^ORCID,Hussain Abrar⁴,Tariq Khan Sidrah¹,Rehman Halimur¹⁵,Hanif Bangash Muhammad⁶,Al Mughairbi Fadwa⁷,Hamid Hamdard Muhammad⁸

Affiliation:

1. Department of Basic Medical Sciences, Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan

2. Department of Physical Therapy, Shifa Tameer-e-Millat University, Islamabad Pakistan

3. Faculty of Pharmacy, Gomal University, Dera Ismail Khan, Pakistan

4. Balochistan University of Information Technology, Engineering and Management Sciences, Pakistan

5. Department of Pharmacology, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan

6. Isotopes Production Division, Pakistan Institute of Nuclear Science & Technology, Islamabad, Pakistan

7. Department of Psychology, United Arab Emirates University Al Ain United Arab Emirates

8. Faculty of Biological Sciences, Kabul University, Kabul Afghanistan

Funder

provided by Shifa Tameer-e-Millat University

Shifa Tameer-e-Millat University, Islamabad

Publisher

Informa UK Limited

Subject

Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology

Link

https://www.tandfonline.com/doi/pdf/10.1080/21655979.2021.1955809

Reference37 articles.

1. PharmGKB summary

2. Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

3. Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian population

4. Genetically modified proteins: functional improvement and chimeragenesis

5. ACCF/AHA Clopidogrel Clinical Alert: Approaches to the FDA “Boxed Warning”

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