CRISPR/cas9-mediated overexpression of long non-coding RNA SRY-box transcription factor 21 antisense divergent transcript 1 regulates the proliferation of osteosarcoma by increasing the expression of mechanistic target of rapamycin kinase and Kruppel like factor 4

Author:

Zhang Weiying1,Wang Qiang2,Du Haibo3,Jiang Shichao456

Affiliation:

1. Health Management Center, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China

2. Department of human resources, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China

3. Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, China

4. Department of orthopedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China

5. Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China

6. Department of orthopedics, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China

Funder

Project of Shandong medical and health science development

Academic promotion pro gramme of Shandong First Medical University

the National Science Foundation of China

Chinese Universities Scientific Fund

Publisher

Informa UK Limited

Subject

Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology

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