Is thrombin a “toxin” in the pathogenesis of preeclampsia?
Author:
Affiliation:
1. Department of Obstetrics, Gynecology and Family Medicine, Hamamatsu University, School of Medicine
Publisher
Japan Society for the Study of Hypertension in Pregnancy
Subject
General Earth and Planetary Sciences,General Engineering,General Environmental Science
Link
https://www.jstage.jst.go.jp/article/jsshp/3/1/3_13/_pdf
Reference43 articles.
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2. 2. Brosens I. A study of the spiral arteries of the decidua basalis in normotensive and hypertensive pregnancies. J Obstet Gynaecol Br Commonw. 1964; 71: 222–230.
3. 3. Gilbert JS, Babcock SA, Granger JP. Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression. Hypertension. 2007; 50: 1142–1147.
4. 4. Nevo O, Soleymanlou N, Wu Y, et al. Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1. Am J Physiol Regul Integr Comp Physiol. 2006; 291: R1085–1093.
5. 5. Cindrova-Davies T, Sanders DA, Burton GJ, Charnock-Jones DS. Soluble FLT1 sensitizes endothelial cells to inflammatory cytokines by antagonizing VEGF receptor-mediated signalling. Cardiovasc Res. 2011; 89: 671–679.
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