Affiliation:
1. Kemerovo State Medical University
2. Kemerovo Regional Center for Hygiene and Epidemiology
3. Research Institute for Complex Issues of Cardiovascular Diseases
Abstract
Aim. To study the trends in the prevalence of respiratory tract infections in the population of Kemerovo Region and to interrogate the particulate matter as a possible route for the transmission of multidrug-resistant microorganisms into medical organisations.Materials and Methods. We investigated the prevalence of acute respiratory infections and community-acquired pneumonia among the population of Kuzbass (Kemerovo Region) according to the offcial medical records collected from 2004 to 2020. The study included 10,320,384 cases of acute respiratory infections, 145,357 cases of community-acquired pneumonia, 344,703 hospitalisations of the adults (subjects ≥ 18 years of age) and 75,041 hospitalisations of children (< 18 years of age). Collection of particulate matter samples (n = 97) was performed using sterile gloves and containers from ventilation grilles and adjacent air ducts of the exhaust ventilation systems in various healthcare settings. Bacterial composition of the dust was examined using a VITEK 2 Compact biochemical analyzer. Viral diversity was screened by polymerase chain reaction.Results. Over the study period, respiratory infections were common in Kemerovo Region (average prevalence 22,155.9 per 100,000 population) and showed an increasing incidence. Frequency of respiratory infections among the hospitalised patients was 207.14 per 1,000, being 1.63-fold higher in children than in adults (304.15 and 186.02, respectively). In 2020, the proportion of cefotaxime-resistant Klebsiella spp. was 26.20% that was strikingly high compared to 2019. Hospital particulate matter frequently (71.13% samples) harboured multidrug-resistant microorganisms.Conclusions. High prevalence and morbidity from respiratory infections in Kemerovo Region are combined with high prevalence and biodiversity of airborne microorganisms, in particular multidrug-resistant microbes contaminating the hospital particulate matter.
Publisher
Kemerovo State Medical University
Reference9 articles.
1. Nagolkin AV, Volodina EV, Zagidullov MF, Akimkin VG, Borisoglebskaya AP, Safatov AS, Kuzin VV, Dmitrieva VA. Modern scientific and practical trends in air disinfection in medical facilities. ZNiSO. 2016;(2):41-51 (in Russ.).
2. Shestopalov NV, Skopin AYu, Fedorova LS, Gololobova TV. Developing methodical approaches to managing risks of airborne infections with aerosol contagion. Health risk analysis. 2019;(1):84-92. (in Russ.). https://doi.org/10.21668/health.risk/2019.1.09
3. О санитарно-эпидемиологической обстановке в Российской Федерации в 2019 году. Государственный доклад. Ссылка активна на 07.03.2021 [O sanitarno-jepidemiologicheskoj obstanovke v Rossijskoj Federacii v 2019 godu. Gosudarstvennyj doklad]. Available at: http://www.rospotrebnadzor.ru/documents/documents.php
4. Gruzdeva O.A., Bilichenko T.N., Vorontsova V.A., Uvarova A.V. Morbidity of infuenza, other acute respiratory viral infections and pneumonia in population of the Central district of Moscow, 2012 - 2016, and vaccine prevention. Russian Pulmonology. 2017;27(6):732-739. (in Russ.). https://doi.org/10.18093/0869-0189-2017-27-6-732-739
5. Orlova NV, Chukaeva II. Modern approaches to therapy of acute respiratory viral infections of the upper respiratory tract. Medical Council. 2017;(5):58-64. (In Russ.). https://doi.org/10.21518/2079-701X-2017-5-58-64