Evaluation of the Alteration in Glucose Production and Metabolism Following Magnesium Usage among Diabetics

Abstract

The study aimed at evaluating the outcome on glucose concentration in some diabetics after measured dose of magnesium has been dispensed for 8 weeks duration. Applying various spectrophotometric methods, the concentration of glucose, glucagon, insulin and C-peptide were measured along with hepatic glucose production and rate of glucose infusion. Values from these parameters were statistically determined. We observed increase in both usage and metabolism following the administration of magnesium. We particularly observed insulin-induced reduction, total body glucose utilization (30.8 ± 0.7 Vs 36.5 ± 0.9 mol/ kg. min. P  0.005) and glucose metabolism (19.0 ± 0.8 Vs 23.2 ± 0.3 mol/ kg. min P  0.01) were raised after magnesium use. It is our conclusion that the use of magnesium at recommended dose could ameliorate glucose metabolism and enhance insulin sensitivity among diabetics.