The enhancement of antibody concentration and achievement of high cell density CHO cell cultivation by adding nucleoside
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Clinical Biochemistry,Biomedical Engineering,Bioengineering,Biotechnology
Link
http://link.springer.com/article/10.1007/s10616-017-0066-7/fulltext.html
Reference46 articles.
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2. Backliwal G, Hildinger M, Kuettel I, Delegrange F, Hacker DL, Wurm FM (2008) Valproic acid: a viable alternative to sodium butyrate for enhancing protein expression in mammalian cell cultures. Biotechnol Bioeng 101:182–189. doi: 10.1002/bit.21882
3. Barnes LM, Bentley CM, Dickson AJ (2000) Advances in animal cell recombinant protein production: GS-NS0 expression system. Cytotechnology 32:109–123. doi: 10.1023/A:1008170710003
4. Bebbington CR, Renner G, Thomson S, King D, Abrams D, Yarranton GT (1992) High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker. Biotechnol (NY) 10:169–175. doi: 10.1038/nbt0292-169
5. Birch JR, Racher AJ (2006) Antibody production. Adv Drug Deliv Rev 58:671–685. doi: 10.1016/j.addr.2005.12.006
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