Effect of transmembrane pressure on Factor VIII yield in ATF perfusion culture for the production of recombinant human Factor VIII co-expressed with von Willebrand factor-Reference-Cited by-同舟云学术

Effect of transmembrane pressure on Factor VIII yield in ATF perfusion culture for the production of recombinant human Factor VIII co-expressed with von Willebrand factor

Published:2015-10-13 Issue:5 Volume:68 Page:1687-1696
ISSN:0920-9069
Container-title:Cytotechnology
language:en
Short-container-title:Cytotechnology

Author:

Kim Seung-Chul,An Sora,Kim Hyun-Ki,Park Beom-Soo,Na Kyu-Heum,Kim Byung-Gee

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Clinical Biochemistry,Biomedical Engineering,Bioengineering,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s10616-015-9918-1.pdf

Reference29 articles.

1. Berntorp E (1997) Second generation, B-domain deleted recombinant factor VIII. Thromb Haemost 78:256–260

2. Boedeker BG (2001) Production processes of licensed recombinant factor VIII preparations. Semin Thromb Hemost 27:385–394

3. Casademunt E, Martinelle K, Jernberg M, Winge S, Tiemeyer M, Biesert L, Knaub S, Walter O, Schroder C (2012) The first recombinant human coagulation factor VIII of human origin: human cell line and manufacturing characteristics. Eur J Haematol 89:165–176

4. Clincke MF, Molleryd C, Zhang Y, Lindskog E, Walsh K, Chotteau V (2013) Very high density of CHO cells in perfusion by ATF or TFF in WAVE bioreactor. Part I. Effect of the cell density on the process. Biotechnol Prog 29:754–767

5. Crowley J, Wubben M, Martin JMC (2012) Process for cell culturing by continuous perfusion and alternating tangential flow. US Patent 8206981 B1

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