Co-culture of the 55-6 B cell hybridoma with the EL-4 thymoma cell. Effect on cell growth and monoclonal antibody production

Author:

Martín-López Alicia,Acosta-López Lourdes,García-Camacho Francisco,Contreras-Gómez Antonio,Molina-Grima Emilio

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Clinical Biochemistry,Biomedical Engineering,Bioengineering,Biotechnology

Reference27 articles.

1. Acosta A, Sánchez A, García F, Contreras A, Molina E (2007) Analysis of kinetic, stoichiometry and regulation of glucose and glutamine metabolism in hybridoma batch cultures using logistic equations. Cytotechnology 54:189–200

2. Bergman MC, Attrep JF, Grammer AC, Lipsky PE (1996) Ligation of CD40 influences the function of human Ig-secreting B cell hybridomas both positively and negatively. J Immunol 156:3118–3132

3. Cohen DC, Mered M, Simmons R, Dadson AC, Figueroa C, Rice CW (1992) Systems for large-scale continuous perfusion of mammalian cells grown in suspension. In: Ladis MR, Bose A (eds) Harnesing biotechnology for the 21st century. American Chemical Society, Washington, pp 211–214

4. Deer JR, Allison DS (2004) High-level expression of proteins in mammalian cells using transcription regulatory sequences from the Chinese hamster EF-1α gene. Biotechnol Prog 20:880–889

5. Figueroa B Jr, Chen S, Oyler GA, Hardwick JM, Betenbaugh MJ (2004) Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. Biotechnol Bioeng 85:589–600

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