Effects of codon optimization, N-terminal truncation and gene dose on the heterologous expression of berberine bridge enzyme-Reference-Cited by-同舟云学术

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Effects of codon optimization, N-terminal truncation and gene dose on the heterologous expression of berberine bridge enzyme

Published:2022-03-22 Issue:5 Volume:38 Page:
ISSN:0959-3993
Container-title:World Journal of Microbiology and Biotechnology
language:en
Short-container-title:World J Microbiol Biotechnol

Author:

Xu Zixuan,Xia Liqiong,Sun Mengshan,Huang Peng,Zeng Jianguo^ORCID

Funder

Hunan Provincial Natural Science Foundation of China

Hunan Provincial Key Research and Development Project

The science and technology innovation Program of Hunan Province

Hunan Innovative Province Construction Special Fund Grant, Yuelu Mountain Seed Industry Innovation Project

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Physiology,Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s11274-022-03265-w.pdf

Reference18 articles.

1. Beaudoin GA, Facchini PJ (2014) Benzylisoquinoline alkaloid biosynthesis in opium poppy. Planta 240(1):19–32. https://doi.org/10.1007/s00425-014-2056-8

2. Bessi I, Bazzicalupi C, Richter C, Jonker HR, Saxena K, Sissi C, Chioccioli M, Bianco S, Bilia AR, Schwalbe H, Gratteri P (2012) Spectroscopic, molecular modeling, and NMR-spectroscopic investigation of the binding mode of the natural alkaloids berberine and sanguinarine to human telomeric G-quadruplex DNA. ACS Chem Biol 7(6):1109–1119. https://doi.org/10.1021/cb300096g

3. Cos O, Serrano A, Montesinos JL, Ferrer P, Cregg JM, Valero F (2005) Combined effect of the methanol utilization (Mut) phenotype and gene dosage on recombinant protein production in Pichia pastoris fed-batch cultures. J Biotechnol 116(4):321–335. https://doi.org/10.1016/j.jbiotec.2004.12.010

4. Fossati E, Ekins A, Narcross L, Zhu Y, Falgueyret JP, Beaudoin GA, Facchini PJ, Martin VJ (2014) Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae. Nat Commun 5:3283. https://doi.org/10.1038/ncomms4283

5. Galanie S, Smolke CD (2015) Optimization of yeast-based production of medicinal protoberberine alkaloids. Microb Cell Fact 14:144. https://doi.org/10.1186/s12934-015-0332-3

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