Comment on: “A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-aspartate Angiotensin I in Healthy Subjects”
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/s40268-016-0155-7.pdf
Reference8 articles.
1. Sim MK. Des-aspartate-angiotensin I, a novel angiotensin AT(1) receptor drug. Eur J Pharmacol. 2015;760:36–41.
2. Lee KO, Khoo CM, Chowbay B, Chan YH, Sim MK. A single dose-escalation study to evaluate the safety and pharmacokinetics of orally administered des-aspartate angiotensin I in healthy subjects. Drugs R D. 2016;16:317–326. doi: 10.1007/s40268-016-0143-y .
3. Loh WM, Ling WC, Murugan DD, et al. Des-aspartate angiotensin I (DAA-I) reduces endothelial dysfunction in the aorta of the spontaneously hypertensive rat through inhibition of angiotensin II-induced oxidative stress. Vascul Pharmacol. 2015;71:151–8.
4. Wong YC, Sim MK, Lee KO. Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice. Biochem Pharmacol. 2011;82:1198–208.
5. Loh WM, Ling WC, Murugan DD, et al. Des-aspartate angiotensin I (DAA-I) reduces endothelial dysfunction in the aorta of the spontaneously hypertensive rat through inhibition of angiotensin II-induced oxidative stress. Vascul Pharmacol. 2015;71:151–8.
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1. Author’s Reply to Srinivas: “A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects”;Drugs in R&D;2016-11-30
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